Association of serum interleukin-27 with the exacerbation of chronic obstructive pulmonary disease

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Association of serum interleukin‐27 with the exacerbation of chronic obstructive pulmonary disease

We have previously demonstrated that chronic obstructive pulmonary disease (COPD) patients who do not have Siglec-14 are less prone to exacerbation of the disease. Siglec-14 is a myeloid cell protein that recognizes bacteria and triggers inflammatory responses. Therefore, soluble mediators secreted by myeloid cells responding to Siglec-14 engagement could be involved in the pathogenesis of exac...

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[Acute exacerbation of chronic obstructive pulmonary disease].

Exacerbation of COPD is a common problem, which causes a considerable burden to the patient and the healthcare system. Management of exacerbations is broadly based on clinical features and severity. Initial clinical evaluation is crucial to define the patients requiring hospital admissions and those that could be managed as outpatients. Medical treatment should follow updated recommendations in...

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ژورنال

عنوان ژورنال: Physiological Reports

سال: 2014

ISSN: 2051-817X

DOI: 10.14814/phy2.12069